Article Abstract

Association of the metformin with the risk of lung cancer: a meta-analysis

Authors: Li Wang, Yong Song, Guan-Nan Wu, Dong-Mei Yuan

Abstract

Objective: To assess the correlation between metformin and risk of developing lung cancer by metaanalysis.
Methods: Papers on the correlation between metformin and risk of lung cancer were searched from PubMed, MEDLINE, EMBASE, ISI Web of Science, and Cochrane Library.
Results: Six papers on case-control study were included in this study, involving 39,787 metformin users and 177,752 controls. Meta-analysis showed that the risk of developing lung cancer was lower in metformin users than in those without metformin (OR=0.55, 95% CI: 0.35-0.85, P<0.001).
Conclusions: The risk of developing lung cancer is lower in metformin users than in those without metformin.

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