Article Abstract

Blocking both epidermal growth factor receptor and mesenchymal-to-epithelial transition pathways in EGFR-mutated lung cancer

Authors: Nagio Takigawa, Nobuaki Ochi, Hiromichi Yamane

Abstract

Although most of epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC) is sensitive to EGFR tyrosine kinase inhibitor (TKI), the tumor becomes resistant to the drug after around 1 year.

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