Advances in clinical trials of targeted therapy and immunotherapy of lung cancer in 2018

Zhengyang Hu, Ming Li, Zhencong Chen, Cheng Zhan, Zongwu Lin, Qun Wang


There were many clinical studies on lung cancer in 2018. In particular, significant progress has been made in immunotherapy and targeted therapy. Whether in small cell lung cancer (SCLC) or non- small cell lung cancer (NSCLC), immune checkpoint inhibitors (ICIs) have shown good results. For patients with specific gene mutations, the new generation inhibitors also showed good results in clinical trials. In this review, we summarize the clinical trials in lung cancer in 2018 and describe the progress and prospects for lung cancer therapies.