Vol 5, No 6 (December 2016): Translational Lung Cancer Research (Emerging Treatment Options for Brain Metastases from Non-small Cell Lung Cancer)

Review Article

Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of central nervous system metastases from non-small cell lung cancer: the present and the future
Claudia Proto, Martina Imbimbo, Rosaria Gallucci, Angela Brissa, Diego Signorelli, Milena Vitali, Marianna Macerelli, Giulia Corrao, Monica Ganzinelli, Francesca Gabriella Greco, Marina Chiara Garassino, Giuseppe Lo Russo
Achievements and future developments of ALK-TKIs in the management of CNS metastases from ALK-positive NSCLC
Lorenza Landi, Federico Cappuzzo
Non-small cell lung cancer (NSCLC) and central nervous system (CNS) metastases: role of tyrosine kinase inhibitors (TKIs) and evidence in favor or against their use with concurrent cranial radiotherapy
Panagiota Economopoulou, Giannis Mountzios
State of the art of chemotherapy for the treatment of central nervous system metastases from non-small cell lung cancer
Alessandro Inno, Vincenzo Di Noia, Ettore D’Argento, Alessandra Modena, Stefania Gori
Anti-angiogenetic therapies for central nervous system metastases from non-small cell lung cancer
Consuelo Buttigliero, Valentina Bertaglia, Silvia Novello
Are immune checkpoint blockade monoclonal antibodies active against CNS metastases from NSCLC?—current evidence and future perspectives
Grainne M. O’Kane, Natasha B. Leighl
Defining the endpoints: how to measure the efficacy of drugs that are active against central nervous system metastases
Alessandra Fabi, Antonello Vidiri

Case Report

A rare case of palatin tonsillar metastasis from small cell lung cancer
Chiara D’Antonio, Alberto Lombardini, Concetta Elisa Onesti, Rosa Falcone, Adriana Romiti, Marianna Lombardi, Salvatore Lauro, Paolo Marchetti
Unexpected long survival of brain oligometastatic non-small cell lung cancer (NSCLC) treated with multimodal treatment: a single-center experience and review of the literature
Concetta Elisa Onesti, Daniela Iacono, Silvia Angelini, Salvatore Lauro, Marco Mazzotta, Mario Alberto Occhipinti, Raffaele Giusti, Paolo Marchetti
Metastatic lymphoepithelioma-like carcinoma of the lung treated with nivolumab: a case report and focused review of literature
Chul Kim, Arun Rajan, Pedro A. Debrito, Giuseppe Giaccone