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Inhibition of MEK, a canonical KRAS pathway effector in KRAS mutant NSCLC

   
@article{TLCR20503,
	author = {Rafael Rosell and Niki Karachaliou and Carles Codony-Servat and Masaoki Ito},
	title = {Inhibition of MEK, a canonical KRAS pathway effector in KRAS mutant NSCLC},
	journal = {Translational Lung Cancer Research},
	volume = {7},
	number = {Suppl 3},
	year = {2018},
	keywords = {},
	abstract = {KRAS mutant NSCLC cells require active nuclear export of Iκβα (also known as NFKBIA), a negative regulatory protein of NF-κB signaling, for maintaining survival signaling (1-3).  Nuclear export receptor XPO1 correlates with KRAS mutation status.},
	issn = {2226-4477},	url = {https://tlcr.amegroups.org/article/view/20503}
}