Vol 10, No 3 (March 2021): Translational Lung Cancer Research

Original Article

Detection and quantification of EGFR T790M mutation in liquid biopsies by droplet digital PCR
Catarina Silveira, Ana Carla Sousa, André Janeiro, Sara Malveiro, Encarnação Teixeira, Eva Brysch, Marcos Pantarotto, Margarida Felizardo, Rosa Madureira, Fernando Nogueira, Cátia Guimarães, Cristina Matos, Dolores Canário, Jácome Bruges-Armas, Maria Carmo-Fonseca
Timing of chronic obstructive pulmonary disease diagnosis in lung cancer prognosis: a clinical and genomic-based study
Jie Dai, Yanqi He, Kunlatida Maneenil, Han Liu, Ming Liu, Qian Guo, Amy C. Bennett, Shawn M. Stoddard, Jason A. Wampfler, Gening Jiang, Ping Yang
Low-level expression of necroptosis factors indicates a poor prognosis of the squamous cell carcinoma subtype of non-small-cell lung cancer
Jun Hyeok Lim, Sekyung Oh, Lucia Kim, Young Ju Suh, Yu-Jin Ha, Jung Soo Kim, Hyun-Jung Kim, Mi Hwa Park, Young Sam Kim, Yunjung Cho, Seung Min Kwak, Hong Lyeol Lee, You-Sun Kim, Jeong-Seon Ryu
Effect of prior therapy on tumor mutational burden in NSCLC
Sushma Jonna, Ari Vanderwalde, Jorge Nieva, Kelsey Anne Poorman, Michelle Saul, Xinyu von Buttlar, John Y. Hu, Stephen V. Liu
Deep sequencing reveals the genomic characteristics of lung adenocarcinoma presenting as ground-glass nodules (GGNs)
Nan Wu, Sixue Liu, Jingjing Li, Zhenyu Hu, Shi Yan, Hongwei Duan, Dafei Wu, Yuanyuan Ma, Shaolei Li, Xing Wang, Yaqi Wang, Xiang Li, Xuemei Lu
Titin mutation in circulatory tumor DNA is associated with efficacy to immune checkpoint blockade in advanced non-small cell lung cancer
Chunxia Su, Xinxin Wang, Juan Zhou, Jing Zhao, Fei Zhou, Guodong Zhao, Xiaohong Xu, Xuan Zou, Bo Zhu, Qingzhu Jia
Inhaled corticosteroids and risk of lung cancer among chronic obstructive pulmonary disease patients: a comprehensive analysis of nine prospective cohorts
Fan Ge, Yi Feng, Zhenyu Huo, Caichen Li, Runchen Wang, Yaokai Wen, Sirui Gao, Haoxin Peng, Xiangrong Wu, Hengrui Liang, Bo Cheng, Ran Zhong, Jianxing He, Wenhua Liang
Concurrent use of metformin enhances the efficacy of EGFR-TKIs in patients with advanced EGFR-mutant non-small cell lung cancer—an option for overcoming EGFR-TKI resistance
Ruoshuang Han, Yijun Jia, Xuefei Li, Chao Zhao, Sha Zhao, Sangtian Liu, Yiwei Liu, Donglai Chen, Qian Zhang, Xiaozhen Liu, Jinpeng Shi, Jiayu Li, Caicun Zhou
Comprehensive molecular analysis of genomic profiles and PD-L1 expression in lung adenocarcinoma with a high-grade fetal adenocarcinoma component
Masaki Suzuki, Rika Kasajima, Tomoyuki Yokose, Hiroyuki Ito, Eigo Shimizu, Seira Hatakeyama, Kazuaki Yokoyama, Rui Yamaguchi, Yoichi Furukawa, Satoru Miyano, Seiya Imoto, Emi Yoshioka, Kota Washimi, Yoichiro Okubo, Kae Kawachi, Shinya Sato, Yohei Miyagi
Validation of multivariable lung cancer risk prediction models for the personalized assignment of optimal screening frequency: a retrospective analysis of data from the German Lung Cancer Screening Intervention Trial (LUSI)
Sandra González Maldonado, Lucas Cory Hynes, Erna Motsch, Claus-Peter Heussel, Hans-Ulrich Kauczor, Hilary A. Robbins, Stefan Delorme, Rudolf Kaaks
Development of RECLS score to predict survival in lung cancer patients with malignant pleural effusion
Tianli Zhang, Xi Chen, Bing Wan, Yangyang Xu, Hongbing Liu, Tangfeng Lv, Ping Zhan, Yong Song
Whole exome sequencing characterization of individuals presenting extreme phenotypes of high and low risk of developing tobacco-induced lung adenocarcinoma
Ana Patiño-García, Elizabeth Guruceaga, Victor Segura, Rodrigo Sánchez Bayona, Maria Pilar Andueza, Ibon Tamayo Uria, Guillermo Serrano, Juan Pablo Fusco, María José Pajares, Alfonso Gurpide, Marimar Ocón, Miguel F. Sanmamed, Maria Rodriguez Ruiz, Ignacio Melero, Maria Dolores Lozano, Carlos de Andrea, Guillermo Pita, Anna Gonzalez-Neira, Alvaro Gonzalez, Javier J. Zulueta, Luis M. Montuenga, Ruben Pio, Jose Luis Perez-Gracia
Tumor-associated macrophages secret exosomal miR-155 and miR-196a-5p to promote metastasis of non-small-cell lung cancer
Xiang Li, Zhipeng Chen, Yaojun Ni, Chengyu Bian, Jingjing Huang, Liang Chen, Xueying Xie, Jun Wang
Public opinion on implementing the National Lung Cancer Screening Program in Korea
Junli Park, Jaeho Lee, Yeol Kim
Examining the diagnostic pathway for lung cancer patients in Wales using discrete event simulation
Tracey J. England, Paul R. Harper, Tom Crosby, Daniel Gartner, Edilson F. Arruda, Kieran G. Foley, Ian J. Williamson
HER2 transmembrane domain mutation: comprehensive characteristics and real-world evidence of treatment response in Chinese lung adenocarcinoma
Ziqi Jia, Jiahua Xing, Ji Li, Weiwei Wang, Yadong Wang, Yang Song, Xiaoying Yang, Jianchao Xue, Junyi Ye, Bing Li, Han Han-Zhang, Jiaxing Zhao, Xiaochun Zhang, Feng Peng, Fengxia Chen, Xueqin Chen, Yan Lu, Shenpeng Ying, Dongping Wu, Xinwei Zhang, Caixia Ma, Lipeng Lai, Songling Ma, Dianjing Liang, Peng Liu, Xiaoguang Li, Naixin Liang, Shanqing Li
Prognostic value of baseline and change in neutrophil-to-lymphocyte ratio for survival in advanced non-small cell lung cancer patients with poor performance status receiving PD-1 inhibitors
Shixue Chen, Ruixin Li, Zhibo Zhang, Ziwei Huang, Pengfei Cui, Wangping Jia, Sujie Zhang, Haitao Tao, Lijie Wang, Xiaoyan Li, Jinliang Wang, Junxun Ma, Zhefeng Liu, Di Huang, Xuan Zheng, Yuichi Saito, Yoshinobu Ichiki, Yi Hu
Surgery for advanced-stage non-small cell lung cancer: lobectomy or sub-lobar resection?
Zhexue Hao, Hengrui Liang, Yichi Zhang, Wei Wei, Yuting Lan, Shuxian Qiu, Guo Lin, Runchen Wang, Yulin Liu, Yingying Chen, Jun Huang, Wei Wang, Fei Cui, Taichiro Goto, Jin Yong Jeong, Giulia Veronesi, Alberto Lopez-Pastorini, Hitoshi Igai, Wenhua Liang, Jianxing He, Jun Liu
Radiotherapy programs neutrophils to an antitumor phenotype by inducing mesenchymal-epithelial transition
Qiqi Liu, Yuying Hao, Rui Du, Dan Hu, Jian Xie, Jingxin Zhang, Guodong Deng, Ning Liang, Tiantian Tian, Lukas Käsmann, Dirk Rades, Chai Hong Rim, Pingping Hu, Jiandong Zhang
Isochorismatase domain-containing protein 1 (ISOC1) participates in DNA damage repair and inflammation-related pathways to promote lung cancer development
Jinghan Shi, Fujun Yang, Nanfeng Zhou, Yan Jiang, Yanfeng Zhao, Junjie Zhu, Arsela Prelaj, Jyoti Malhotra, Nicola Normanno, Elisa Danese, Andrés F. Cardona, Xuan Hong, Gening Jiang, Xiao Song
circFBXW7 attenuates malignant progression in lung adenocarcinoma by sponging miR-942-5p
Yanting Dong, Tong Qiu, Yunpeng Xuan, Ao Liu, Xiao Sun, Zhangfeng Huang, Wenhao Su, Wenxing Du, Tianxiang Yun, Yang Wo, Alfons Navarro, Wenjie Jiao
The effectiveness of three-dimensional reconstruction in the localization of multiple nodules in lung specimens: a prospective cohort study
Ying Ji, Tao Zhang, Lin Yang, Xin Wang, Linlin Qi, Fengwei Tan, Jean H. T. Daemen, Erik R. de Loos, Bin Qiu, Shugeng Gao
A signature of estimate-stromal-immune score-based genes associated with the prognosis of lung adenocarcinoma
Qianli Ma, Yang Chen, Fei Xiao, Yang Hao, Zhiyi Song, Jin Zhang, Katsuhiro Okuda, Sang-Won Um, Mario Silva, Yoshihisa Shimada, Chaozeng Si, Chaoyang Liang
Increased detection of circulating tumor DNA by short fragment enrichment
Yang Liu, Yangyang Liu, Yingying Wang, Lei Li, Wenjun Yao, Yingnan Song, Bing Liu, Weihuang Chen, Mariacarmela Santarpia, Elisabetta Rossi, Rita Zamarchi, Zhe Wang, Qiming Wang, Gang Cheng
High discrepancy in thrombotic events in non-small cell lung cancer patients with different genomic alterations
Yiwei Liu, Wanying Wang, Fengying Wu, Guanghui Gao, Jian Xu, Xuefei Li, Chao Zhao, Shuo Yang, Shiqi Mao, Yingying Pan, Keyi Jia, Chuchu Shao, Bin Chen, Shengxiang Ren, Caicun Zhou
Concomitant mutation status of ALK-rearranged non-small cell lung cancers and its prognostic impact on patients treated with crizotinib
Jingjing Li, Bin Zhang, Yu Zhang, Feng Xu, Zhenfa Zhang, Lin Shao, Chunhe Yan, Paola Ulivi, Marc G. Denis, Petros Christopoulos, Vincent Thomas de Montpréville, Eric H. Bernicker, Anthonie J. van der Wekken, Changli Wang, Dongsheng Yue