Home - Translational Lung Cancer Research

New Impact Factor for Translational Lung Cancer Research: 4.726

We are pleased to announce that the Translational Lung Cancer Research (TLCR) has attained its latest impact factor update for the 2021 citation year: 4.726.

Interviews with Outstanding Authors (2022)

In 2022, many authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors, with a brief interview of their thoughts and insights as authors. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

ALK-Positive NSCLC (Ongoing)

This special series on “ALK-Positive NSCLC” is edited by Dr. Justin F. Gainor and Dr. Jessica J. Lin from the Department of Medicine, Harvard Medical School, Boston, USA. This special series aims to provide an updated overview of the most recent acquisitions and future perspectives.

TLCR Annual Report 2021

Welcome to the 2021 annual report for Translational Lung Cancer Research. In 2021, the TLCR has continued its mission to increase the quality and impact of the journal, and to provide readers with a novel, well-organized, informative, enlightening and educational journal.

We would like to sincerely thank our Editorial Board Members, Guest editors, Reviewers, Authors, Readers for all your supports and contributions to TLCR in 2021, and we look forward to continuing our work with you in the new year.

Reviewer of the Month (2022)

In 2022, TLCR reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

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Vol 11, No 11 (November, 2022)

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TLCR Chinese Edition more

免疫治疗是晚期非小细胞肺癌去化疗的关键，或还是未到时候？

免疫检查点抑制剂（immune checkpoint... More >>

晚期或转移性非小细胞肺癌一线免疫治疗中，肿瘤细胞PD-L1表达的阈值究竟在哪

对于晚期或转移性非小细胞肺癌（non-small cell lung... More >>

KEYNOTE-042研究：降低帕博利珠单抗单药一线治疗的PD-L1阈值是个好主意吗？

在针对程序性死亡1（programmed death 1，PD-1）或程序性死亡配体1（programmed... More >>

Editorial

Multiple mutations in the EGFR gene in lung cancer is rare but should not be forgettable

Ryo Miyata, Masatsugu Hamaji

PDF Pages: 2167-2169 Full Text (59) COI Form Open Access

Re-administration of immune checkpoint inhibitors for patients with non-small cell lung cancer

Taiki Hakozaki

PDF Pages: 2170-2174 Full Text (45) COI Form Open Access

Targeted intraoperative fluorescence imaging for the visualization of ground-glass nodules in the lung

Hak Soo Choi, Jun Hee Lee, Hyun Koo Kim

PDF Pages: 2175-2177 Full Text (29) COI Form Open Access

What is the real value of predictive models?

Maria Rodriguez, Lucia Milla

PDF Pages: 2178-2180 Full Text (26) COI Form Open Access

Original Article

Development and verification of new monoclonal orthopedia homeobox (OTP) specific antibodies for pulmonary carcinoid diagnostics

Laura Moonen, Jules L. Derks, Lisa M. V. Lap, Britney J. C. A. Marijnissen, Lisa M. Hillen, Michael A. den Bakker, Jan H. von der Thüsen, Robert-Jan van Suylen, Wim Timens, Maria Bintanel, Eugenia Kuteeva, Anne-Marie C. Dingemans, Ernst-Jan M. Speel

PDF Pages: 2181-2191 Full Text (49) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Immune profile analysis of peripheral blood and tumors of lung cancer patients treated with immune checkpoint inhibitors

Yoshinobu Ichiki, Takashi Fukuyama, Mari Ueno, Yoshiro Kanasaki, Hidenori Goto, Mai Takahashi, Shuji Mikami, Noritada Kobayashi, Kozo Nakanishi, Shinichi Hayashi, Tsuyoshi Ishida

PDF Pages: 2192-2207 Full Text (39) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Association of thyroid transcription factor-1 (TTF-1) expression with efficacy of PD-1/PD-L1 inhibitors plus pemetrexed and platinum chemotherapy in advanced non-squamous non-small cell lung cancer

Ritsu Ibusuki, Yasuto Yoneshima, Mikiko Hashisako, Norikazu Matsuo, Taishi Harada, Yuko Tsuchiya-Kawano, Junji Kishimoto, Keiichi Ota, Yoshimasa Shiraishi, Eiji Iwama, Kentaro Tanaka, Yoshinao Oda, Isamu Okamoto

PDF Pages: 2208-2215 Full Text (37) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

ADK-VR2, a cell line derived from a treatment-naïve patient with SDC4-ROS1 fusion-positive primarily crizotinib-resistant NSCLC: a novel preclinical model for new drug development of ROS1-rearranged NSCLC

Francesca Ruzzi, Stefania Angelicola, Lorena Landuzzi, Elena Nironi, Maria Sofia Semprini, Laura Scalambra, Annalisa Altimari, Elisa Gruppioni, Michelangelo Fiorentino, Francesca Giunchi, Manuela Ferracin, Annalisa Astolfi, Valentina Indio, Andrea Ardizzoni, Francesco Gelsomino, Patrizia Nanni, Pier-Luigi Lollini, Arianna Palladini

PDF Pages: 2216-2229 Full Text (28) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Multimodal therapy of epithelioid pleural mesothelioma: improved survival by changing the surgical treatment approach

Laura V. Klotz, Hans Hoffmann, Rajiv Shah, Florian Eichhorn, Christiane Gruenewald, Elena L. Bulut, Raffaella Griffo, Thomas Muley, Petros Christopoulos, Philip Baum, Peter Huber, Seyer Safi, Marc Kriegsmann, Michael Thomas, Helge Bischoff, Hauke Winter, Martin E. Eichhorn

PDF Pages: 2230-2242 Full Text (25) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Multi-omics consensus portfolio to refine the classification of lung adenocarcinoma with prognostic stratification, tumor microenvironment, and unique sensitivity to first-line therapies

Yanmei Zou, Chenlin Cao, Yali Wang, Yilu Zhou, Shuo Yao, Lili Zhang, Kun Zheng, Hong Zhang, Wan Qin, Kai Qin, Huihua Xiong, Xianglin Yuan, Shengling Fu, Yihua Wang, Hua Xiong

PDF Pages: 2243-2260 Full Text (54) Reporting Checklist COI Form Open Access

Development and validation of the artificial intelligence (AI)-based diagnostic model for bronchial lumen identification

Ying Li, Xiaoxuan Zheng, Fangfang Xie, Lin Ye, Elena Bignami, Yasmeen K. Tandon, María Rodríguez, Yun Gu, Jiayuan Sun

PDF Pages: 2261-2274 Full Text (180) Reporting Checklist Data Sharing Statement COI Form Open Access

Establishment and validation of a nomogram model for predicting postoperative recurrence-free survival in stage IA3 lung adenocarcinoma: a retrospective cohort study

Shaobin Yu, Chengxiong You, Renhe Yan, Hui Chen, Chao Chen, Shaojun Xu, Michel Gonzalez, Ruiqin Chen, Mingqiang Kang, Shuchen Chen

PDF Pages: 2275-2288 Full Text (27) Reporting Checklist Data Sharing Statement COI Form Open Access

Safety and efficacy of immunotherapy rechallenge following checkpoint inhibitor-related pneumonitis in advanced lung cancer patients: a retrospective multi-center cohort study

Xinqing Lin, Haiyi Deng, Tianqing Chu, Likun Chen, Yilin Yang, Guihuan Qiu, Xiaohong Xie, Yinyin Qin, Ming Liu, Zhanhong Xie, Ming Ouyang, Shiyue Li, Yong Song, Francesco Petrella, Marko Jakopovic, Nikolaos Tsoukalas, Piergiorgio Solli, Taichiro Goto, Yuichi Saito, Chengzhi Zhou

PDF Pages: 2289-2305 Full Text (32) Reporting Checklist Data Sharing Statement COI Form Open Access

Treatment response and safety of immunotherapy for advanced non-small cell lung cancer with comorbid chronic obstructive pulmonary disease: a retrospective cohort study

Kening Zhang, Chengzhi Zhou, Jiabo Gao, Pei Yu, Xinqing Lin, Xiaohong Xie, Ming Liu, Jiexia Zhang, Zhanhong Xie, Fei Cui, Shiyue Li, Francesco Passiglia, Giulia Maria Stella, Yinyin Qin

PDF Pages: 2306-2317 Full Text (45) Reporting Checklist Data Sharing Statement COI Form Open Access

Consensus

Expert consensus on indocyanine green fluorescence imaging for thoracoscopic lung resection (The Version 2022)

Fei Cui, Jun Liu, Ming Du, Junqiang Fan, Junke Fu, Qing Geng, Ming He, Jian Hu, Bin Li, Shanqing Li, Xukai Li, Yong-De Liao, Ling Lin, Feng Liu, Jian Liu, Junhong Lv, Qiang Pu, Lijie Tan, Hui Tian, Mingsong Wang, Tao Wang, Li Wei, Chuan Xu, Shidong Xu, Shun Xu, Haoxian Yang, Ben-Tong Yu, Guangmao Yu, Zhentao Yu, Chang Young Lee, Eugenio Pompeo, Feredun Azari, Hitoshi Igai, Hyun Koo Kim, Marco Andolfi, Masatsugu Hamaji, Massimiliano Bassi, Wolfram Karenovics, Yojiro Yutaka, Yoshihisa Shimada, Yukinori Sakao, Alan D. L. Sihoe, Yi Zhang, Zhenfa Zhang, Jun Zhao, Wenzhao Zhong, Yuming Zhu, Jianxing He

PDF Pages: 2318-2331 Full Text (254) COI Form Open Access

Review Article

Onco-biome in pharmacotherapy for lung cancer: a narrative review

Akiko T. Tateishi, Yusuke Okuma

PDF Pages: 2332-2345 Full Text (18) Reporting Checklist Peer Review File COI Form Open Access

iMDT Corner

Immune thrombocytopenia in a small cell lung cancer patient treated with atezolizumab: a case report

Guihuan Qiu, Suyang Li, Bingliang Li, Qingqing Yang, Haiyi Deng, Yilin Yang, Xiaohong Xie, Xinqing Lin, Nobuhiko Seki, Satoru Miura, Takehito Shukuya, Chengzhi Zhou, Ming Liu

PDF Pages: 2346-2355 Full Text (41) Reporting Checklist COI Form Open Access

Letter to the Editor

Another point of view for meta-analysis studies focused on protective inhaled corticosteroids and the risk of lung cancer

Gabriel Costa de Carvalho

PDF Pages: 2356-2357 Full Text (26) COI Form Open Access

Erratum

Erratum to NOTCH alteration in EGFR-mutated lung adenocarcinoma leads to histological small-cell carcinoma transformation under EGFR-TKI treatment

Editorial Office

PDF Pages: 2358-2359 Full Text (25) Open Access

Review Article

Targeted therapy for non-small cell lung cancer: current standards and the promise of the future

Bryan A. Chan, Brett G.M. Hughes

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer

Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto

Global trends of lung cancer mortality and smoking prevalence

Farhad Islami, Lindsey A. Torre, Ahmedin Jemal

Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations—a review

Erin L. Stewart, Samuel Zhixing Tan, Geoffrey Liu, Ming-Sound Tsao

Tackling ALK in non-small cell lung cancer: the role of novel inhibitors

Francesco Facchinetti, Marcello Tiseo, Massimo Di Maio, Paolo Graziano, Emilio Bria, Giulio Rossi, Silvia Novello

Circulating tumor cells versus circulating tumor DNA in lung cancer—which one will win?

Silvia Calabuig-Fariñas, Eloísa Jantus-Lewintre, Alejandro Herreros-Pomares, Carlos Camps

Editorial

Whacking a mole-cule: clinical activity and mechanisms of resistance to third generation EGFR inhibitors in EGFR mutated lung cancers with EGFR-T790M

Daniel B. Costa, Susumu S. Kobayashi

Review Articles

Management of ground-glass opacities: should all pulmonary lesions with ground-glass opacity be surgically resected?

Yoshihisa Kobayashi, Tetsuya Mitsudomi

KRAS mutant NSCLC, a new opportunity for the synthetic lethality therapeutic approach

Javier de Castro Carpeño, Cristóbal Belda-Iniesta

Review Article on Lung Cancer Diagnostics and Treatments 2015: A Renaissance of Patient Care

Immune checkpoint inhibitors in clinical practice: update on management of immune-related toxicities

Jeryl Villadolid, Asim Amin

Review Article

Targeted therapy for non-small cell lung cancer: current standards and the promise of the future

Bryan A. Chan, Brett G.M. Hughes

Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations—a review

Erin L. Stewart, Samuel Zhixing Tan, Geoffrey Liu, Ming-Sound Tsao

Global trends of lung cancer mortality and smoking prevalence

Farhad Islami, Lindsey A. Torre, Ahmedin Jemal

Recurrence after surgery in patients with NSCLC

Hidetaka Uramoto, Fumihiro Tanaka

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer

Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto

Non-small cell lung cancer: current treatment and future advances

Cecilia Zappa, Shaker A. Mousa

Phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin (PI3K-Akt-mTOR) signaling pathway in non-small cell lung cancer

Po Yee Yip

Lung cancer molecular epidemiology in China: recent trends

Caicun Zhou

The role of the immune system in non-small cell lung carcinoma and potential for therapeutic intervention

Joanna Domagala-Kulawik

Concordance of IHC, FISH and RT-PCR for EML4-ALK rearrangements

Cristina Teixidó, Niki Karachaliou, Vicente Peg, Ana Gimenez-Capitan, Rafael Rosell

ALK and crizotinib: after the honeymoon…what else? Resistance mechanisms and new therapies to overcome it

Christian Rolfo, Francesco Passiglia, Marta Castiglia, Luis E. Raez, Paul Germonpre, Ignacio Gil-Bazo, Karen Zwaenepoel, Annemieke De Wilde, Giuseppe Bronte, Antonio Russo, Jan P. Van Meerbeeck, Paul Van Schil, Patrick Pauwels

Highlighted Reports in European Lung Cancer Conference

Preoperative mediastinal lymph node staging for non-small cell lung cancer: 2014 update of the 2007 ESTS guidelines

Paul De Leyn, Christophe Dooms, Jaroslaw Kuzdzal, Didier Lardinois, Bernward Passlick, Ramon Rami-Porta, Akif Turna, Paul Van Schil, Frederico Venuta, David Waller, Walter Weder, Marcin Zielinski

Review Article on Lung Cancer Diagnostics and Treatments 2015: A Renaissance of Patient Care

Immune checkpoint inhibitors in clinical practice: update on management of immune-related toxicities

Jeryl Villadolid, Asim Amin

Circulating DNA in diagnosis and monitoring EGFR gene mutations in advanced non-small cell lung cancer

Paola Bordi, Marzia Del Re, Romano Danesi, Marcello Tiseo

Novel radiotherapy approaches for lung cancer: combining radiation therapy with targeted and immunotherapies

Charles B. Simone II, Stuart H. Burri, John H. Heinzerling

Angiogenesis inhibition as a therapeutic strategy in non-small cell lung cancer (NSCLC)

Richard D. Hall, Tri M. Le, Daniel E. Haggstrom, Ryan D. Gentzler

Original Article

Prognostic value of Twist in lung cancer: systematic review and meta-analysis

Junli Zeng, Ping Zhan, Guannan Wu, Wen Yang, Wenjun Liang, Tangfeng Lv, Yong Song

BRAF mutations in non-small cell lung cancer

Peter P. Luk, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina Selinger, Trina Lum, Steven Kao, Sandra A. O’Toole, Wendy A. Cooper

The suitability of small biopsy and cytology specimens for EGFR and other mutation testing in non-small cell lung cancer

Shu Wang, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina I. Selinger, Sandra A. O’Toole, Wendy A. Cooper

Itraconazole can inhibit malignant pleural effusion by suppressing lymphangiogenesis in mice

Yunfen Wang, Yanwen Yao, Hongbin Liu, Xingqun Ma, Tangfeng Lv, Dongmei Yuan, Xinwu Xiao, Jie Yin, Yong Song

Ratio of maximum standardized uptake value to primary tumor size is a prognostic factor in patients with advanced non-small cell lung cancer

Fangfang Chen, Yanwen Yao, Chunyan Ma, Xingqun Ma, Zhaofeng Wang, Tangfeng Lv, Xinwu Xiao, Jie Yin, Yong Song

Advanced proton beam dosimetry part II: Monte Carlo vs. pencil beam-based planning for lung cancer

Dominic Maes, Jatinder Saini, Jing Zeng, Ramesh Rengan, Tony Wong, Stephen R. Bowen

The cytokinesis-blocked micronucleus assay as a novel biomarker for selection of lung cancer screening participants

Randa A. El-Zein, Carol J. Etzel, Reginald F. Munden

The use of TCP based EUD to rank and compare lung radiotherapy plans: in-silico study to evaluate the correlation between TCP with physical quality indices

Abdulhamid Chaikh, Jacques Balosso

Review Article

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer

Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto

Overview of clinicopathologic features of ALK-rearranged lung adenocarcinoma and current diagnostic testing for ALK rearrangement

Hyojin Kim, Jin-Haeng Chung

Neoadjuvant and adjuvant epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for lung cancer

Haoran Zhai, Wenzhao Zhong, Xuening Yang, Yi-Long Wu

Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations—a review

Erin L. Stewart, Samuel Zhixing Tan, Geoffrey Liu, Ming-Sound Tsao

Clinical trials for lung cancer in China

Fei-Yu Niu, Wen-Zhao Zhong, Qing Zhou, Yi-Long Wu

Recurrence after surgery in patients with NSCLC

Hidetaka Uramoto, Fumihiro Tanaka

Prognostic markers in lung cancer: is it ready for prime time?

Chang-Qi Zhu, Ming-Sound Tsao

Potential biomarkers for lung cancer screening

Gabriella Sozzi, Mattia Boeri

Particle therapy in non-small cell lung cancer

Zhongxing Liao, Charles B. Simone II

Computer Aided Nodule Analysis and Risk Yield (CANARY) characterization of adenocarcinoma: radiologic biopsy, risk stratification and future directions

Ryan Clay, Srinivasan Rajagopalan, Ronald Karwoski, Fabien Maldonado, Tobias Peikert, Brian Bartholmai

Immunotherapy and radiation therapy for operable early stage and locally advanced non-small cell lung cancer

Neil K. Taunk, Andreas Rimner, Melissa Culligan, Joseph S. Friedberg, Julie Brahmer, Jamie Chaft

Combining immunotherapy and radiation therapy for small cell lung cancer and thymic tumors

Suchit H. Patel, Andreas Rimner, Roger B. Cohen

Intraoperative near-infrared imaging of mesothelioma

Gregory Thomas Kennedy, Andrew Newton, Jarrod Predina, Sunil Singhal

BAP1, a tumor suppressor gene driving malignant mesothelioma

Mitchell Cheung, Joseph R. Testa

Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation

Jonathan E. Schoenhals, Steven N. Seyedin, Clark Anderson, Eric D. Brooks, Yun R. Li, Ahmed I. Younes, Sharareh Niknam, Ailin Li, Hampartsoum B. Barsoumian, Maria Angelica Cortez, James W. Welsh

Diagnostic and prognostic biomarkers for malignant mesothelioma: an update

Zhongjian Chen, Giovanni Gaudino, Harvey I. Pass, Michele Carbone, Haining Yang

Immunotherapy for malignant pleural mesothelioma: current status and future directions

Jordan Dozier, Hua Zheng, Prasad S. Adusumilli

Biology and clinical significance of circulating tumor cell subpopulations in lung cancer

Linda O’Flaherty, Harriet Wikman, Klaus Pantel

Routine clinical use of circulating tumor cells for diagnosis of mutations and chromosomal rearrangements in non-small cell lung cancer—ready for prime-time?

Emma Pailler, Vincent Faugeroux, Marianne Oulhen, Cyril Catelain, Françoise Farace

Challenges and unanswered questions for the next decade of circulating tumour cell research in lung cancer

Sumitra Mohan, Francesca Chemi, Ged Brady

Biophysical technologies for understanding circulating tumor cell biology and metastasis

Derrick W. Su, Jorge Nieva

Clinical utility of circulating tumor cells in patients with non-small-cell lung cancer

Marianna Gallo, Antonella De Luca, Monica Rosaria Maiello, Amelia D’Alessio, Claudia Esposito, Nicoletta Chicchinelli, Laura Forgione, Maria Carmela Piccirillo, Gaetano Rocco, Alessandro Morabito, Gerardo Botti, Nicola Normanno

Integrating immunotherapy into chemoradiation regimens for medically inoperable locally advanced non-small cell lung cancer

Salma K. Jabbour, Abigail T. Berman, Charles B. Simone II

Editorial

An alternative way to initiate Notch1 signaling in non-small cell lung cancer

Yi-Lin Yang, David Jablons, Liang You

Combination MET- and EGFR-directed therapy in MET-overexpressing non-small cell lung cancers: time to move on to better biomarkers?

Fernando C. Santini, Siddharth Kunte, Alexander Drilon

Systematic Review and Meta-analysis

Association of the metformin with the risk of lung cancer: a meta-analysis

Li Wang, Yong Song, Guan-Nan Wu, Dong-Mei Yuan

China Lung Cancer Research Highlight

Dll4/Notch1 signaling from tip/stalk endothelial cell specification to stroma-dependent lung tumor inhibition: a flavor of Dll4/Notch1 pleiotropy in tumor cell biology

Maria Felice Brizzi, Paola Defilippi

Editorials

Dulanermin in cancer therapy: Still much to do

Cristina Quintavalle, Gerolama Condorelli

Review Articles

EGFR molecular testing in African-American non-small cell lung cancer patients - a review of discrepant data

Bradley T. Clifford, Pingfu Fu, Nathan A. Pennell, Balazs Halmos, Rom S. Leidner

Copy number gains of FGFR1 and 3q chromosome in squamous cell carcinoma of the lung

Pedro Mendez, Jose Luis Ramirez

Role of HGF/MET axis in resistance of lung cancer to contemporary management

Kanwal Pratap Singh Raghav, Ana Maria Gonzalez-Angulo, George R. Blumenschein Jr

Circulating soluble intercellular adhesion Molecule-1 in lung cancer: a systematic review

Xiaoling Gu, Chunyan Ma, Dongmei Yuan, Yong Song

Ceritinib

Clinical development and approval of second generation ALK inhibitors for ALK rearranged lung cancer

Daniel B. Costa

Onartuzumab plus erlotinib

Targeting MET in NSCLC: looking for a needle in a haystack

Lorenza Landi, Federico Cappuzzo

Nivolumab

Nivolumab (anti-PD-1, BMS-936558, ONO-4538) in patients with advanced non-small cell lung cancer

Arun Rajan, James L. Gulley

Brief Report

The role of Imaging and Radiation Oncology Core for precision medicine era of clinical trial

Ying Xiao, Mark Rosen

Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer

Biology of invasive mucinous adenocarcinoma of the lung

Yoon Jin Cha, Hyo Sup Shim

Immunohistochemistry for predictive biomarkers in non-small cell lung cancer

Mari Mino- Kenudson

Below are the latest Translational Lung Cancer Research articles published online ahead of print publication.

Original Article

Effectiveness and safety of opioids for dyspnea in patients with lung cancer: secondary analysis of multicenter prospective observational study

Yoshihiko Taniguchi, Yoshinobu Matsuda, Masanori Mori, Madoka Ito, Tomoo Ikari, Akihiro Tokoro, Sayo Aiki, Shunya Hoshino, Daisuke Kiuchi, Kozue Suzuki, Yuko Igarashi, Takuya Odagiri, Kiyofumi Oya, Emi Kubo, Takashi Yamaguchi

Impact of image filtering and assessment of volume-confounding effects on CT radiomic features and derived survival models in non-small cell lung cancer

Stefania Volpe, Lars Johannes Isaksson, Mattia Zaffaroni, Matteo Pepa, Sara Raimondi, Francesca Botta, Giuliana Lo Presti, Maria Giulia Vincini, Cristiano Rampinelli, Marta Cremonesi, Filippo de Marinis, Lorenzo Spaggiari, Sara Gandini, Matthias Guckenberger, Roberto Orecchia, Barbara Alicja Jereczek-Fossa

SP142 evaluation contributes to the prediction of immune checkpoint inhibitor efficacy in non-small cell lung cancer with high PD-L1 expression assessed by 22C3

Kenji Nakahama, Masahiko Osawa, Motohiro Izumi, Naoki Yoshimoto, Akira Sugimoto, Hiroaki Nagamine, Koichi Ogawa, Yoshiya Matsumoto, Kenji Sawa, Yoko Tani, Hiroyasu Kaneda, Shigeki Mitsuoka, Tetsuya Watanabe, Kazuhisa Asai, Tomoya Kawaguchi

Review Article

A multidisciplinary approach to the work up and management of pulmonary carcinoid tumors and DIPNECH: a narrative review

Robert A. Ramirez, Amanda S. Cass, Satya Das, See-Wei Low, Mitra Mehrad, Otis B. Rickman, Philip M. Scherer, Katharine E. Thomas, Erin A. Gillaspie

Role of ctDNA for the detection of minimal residual disease in resected non-small cell lung cancer: a systematic review

Michela Verzè, Monica Pluchino, Alessandro Leonetti, Matilde Corianò, Francesco Bonatti, Maria P. Armillotta, Fabiana Perrone, Miriam Casali, Roberta Minari, Marcello Tiseo

Case Report

Three non-small cell lung cancer patients who developed pulmonary thromboses during osimertinib treatment and could safely resume concomitant anticoagulation treatment: a report of three cases

Satoshi Shoji, Satoshi Watanabe, Yusuke Hanazawa, Toshiya Fujisaki, Toshiaki Kikuchi

Erratum

Erratum to clinical features and prognosis of resectable pulmonary primary invasive mucinous adenocarcinoma

Editorial Office

Journal Highlight more

Translational Lung Cancer Research is an international, peer-reviewed, open-access journal indexed by Science Citation Index Expanded (SCIE) and PubMed/PubMed Central, focusing on cutting-edge development on the transition from preclinical to clinical research, including but not limited to multimodality therapy, markers, imaging, tumor biology, pathology, chemoprevention, and technical advances related to lung cancer and relevant thoracic diseases.