Original Article

In small cell lung cancer patients treated with RRx-001, a downregulator of CD47, decreased expression of PD-L1 on circulating tumor cells significantly correlates with clinical benefit

Yusuke Tomita, Bryan Oronsky, Nacer Abrouk, Pedro Cabrales, Tony R. Reid, Min-Jung Lee, Akira Yuno, Jonathan Baker, Sunmin Lee, Jane B. Trepel

Open Access

Performance of various risk prediction models in a large lung cancer screening cohort in Gdańsk, Poland—a comparative study

Marcin Ostrowski, Franciszek Bińczyk, Tomasz Marjański, Robert Dziedzic, Sylwia Pisiak, Sylwia Małgorzewicz, Mariusz Adamek, Joanna Polańska, Witold Rzyman

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Hyponatremia as a prognostic factor in non-small cell lung cancer: a systematic review and meta-analysis

Birgitte Sandfeld-Paulsen, Ninna Aggerholm-Pedersen, Anne Winther-Larsen

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A large real-world cohort study of examined lymph node standards for adequate nodal staging in early non-small cell lung cancer

Zhihua Zhu, Zhengbo Song, Wenjie Jiao, Weijian Mei, Chunwei Xu, Qinghua Huang, Chaolun An, Jianguang Shi, Wenxian Wang, Guiping Yu, Pingli Sun, Yinbin Zhang, Jianfei Shen, Yong Song, Jun Qian, Wang Yao, Han Yang, written on behalf of AME Lung Cancer Collaborative Group

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Comprehensive genomic profiling of combined small cell lung cancer

Jing Zhang, Liping Zhang, Jie Luo, Tao Ge, Pengyu Fan, Liangdong Sun, Likun Hou, Junqiang Li, Huansha Yu, Chunxiao Wu, Yuming Zhu, Chunyan Wu, Gening Jiang, Giancarlo Troncone, Jyoti Malhotra, Katsuhiro Okuda, Mariacarmela Santarpia, Rita Zamarchi, Taichiro Goto, Andrés F. Cardona, Jianfang Xu, Qiankun Chen, Zhonghong Zhang, Peng Zhang, written on behalf of the AME Lung Cancer Collaborative Group

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A nomogram prognostic model for large cell lung cancer: analysis from the Surveillance, Epidemiology and End Results Database

Gang Lin, Kang Qi, Bing Liu, Haibo Liu, Jian Li

Open Access

Programmed death-ligand 1 expression level as a predictor of EGFR tyrosine kinase inhibitor efficacy in lung adenocarcinoma

Minsu Kang, Changhee Park, Se Hyun Kim, Sock Won Yoon, Koung Jin Suh, Yu Jung Kim, Chan-Young Ock, Miso Kim, Bhumsuk Keam, Tae Min Kim, Dong-Wan Kim, Dae Seog Heo, Jong Seok Lee

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Immune checkpoint inhibitors in oncogene-addicted non-small cell lung cancer: a systematic review and meta-analysis

Giorgia Guaitoli, Marcello Tiseo, Massimo Di Maio, Luc Friboulet, Francesco Facchinetti

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An immune-related gene expression signature predicts brain metastasis in lung adenocarcinoma patients after surgery: gene expression profile and immunohistochemical analyses

Young Wha Koh, Jae-Ho Han, Seokjin Haam, Hyun Woo Lee

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In small cell lung cancer patients treated with RRx-001, a downregulator of CD47, decreased expression of PD-L1 on circulating tumor cells significantly correlates with clinical benefit

Yusuke Tomita, Bryan Oronsky, Nacer Abrouk, Pedro Cabrales, Tony R. Reid, Min-Jung Lee, Akira Yuno, Jonathan Baker, Sunmin Lee, Jane B. Trepel

Open Access

Apatinib with etoposide capsules as a third- or further-line therapy for extensive-stage small cell lung cancer: an open-label, multicenter, single-arm phase II trial

Zhen He, Hanqiong Zhou, Junsheng Wang, Ding Li, Xudong Zhang, Pengyuan Wang, Tianjiang Ma, Yueqiang Zhang, Chuntao Tian, Yunfang Chen, Minglei Zou, Yu Han, Cong Xu, Shuxiang Ma, Lili Wang, Xuan Wu, Gongbin Chen, Qiming Wang

Open Access

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Review Article

Lung cancer screening: who pays? who receives?—the Chinese perspective

Yang Zhang, Haiquan Chen

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Challenges in the target volume definition of lung cancer radiotherapy

Susan Mercieca, José S. A. Belderbos, Marcel van Herk

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Radiotherapy for thymic epithelial tumours: a review

Krisztian Süveg, Paul Martin Putora, Markus Joerger, Thomas Iseli, Galina Farina Fischer, Karlheinz Ammann, Markus Glatzer

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Novel patterns of progression upon immunotherapy in other thoracic malignancies and uncommon populations

Roberto Ferrara, Diego Signorelli, Claudia Proto, Arsela Prelaj, Marina Chiara Garassino, Giuseppe Lo Russo

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Overdiagnosis in lung cancer screening

David F. Yankelevitz, Claudia I. Henschke

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Pulmonary nodule radiological diagnostic algorithm in lung cancer screening

Katarzyna Dziadziuszko, Edyta Szurowska

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Should sublobar resection be offered for screening-detected lung nodules?

Alan D. L. Sihoe

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Current and future biomarkers for outcomes with immunotherapy in non-small cell lung cancer

Boris Duchemann, Jordi Remon, Marie Naigeon, Lydie Cassard, Jean Mehdi Jouniaux, Lisa Boselli, Jonathan Grivel, Edouard Auclin, Aude Desnoyer, Benjamin Besse, Nathalie Chaput

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An overview of the published and running randomized phase 3 clinical results of radiotherapy in combination with immunotherapy

Ben G. L. Vanneste, Evert J. Van Limbergen, Kobe Reynders, Dirk De Ruysscher

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A narrative review of invasive diagnostics and treatment of early lung cancer

Robert Dziedzic, Tomasz Marjański, Witold Rzyman

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Managing of screening-detected sub-solid nodules—a European perspective

Sara Ricciardi, Richard Booton, Renè Horsleben Petersen, Maurizio Infante, Marco Scarci, Giulia Veronesi, Giuseppe Cardillo

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Screen-detected solid nodules: from detection of nodule to structured reporting

Mario Silva, Gianluca Milanese, Roberta E. Ledda, Ugo Pastorino, Nicola Sverzellati

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Prophylactic cranial irradiation in SCLC

Rafal Suwinski

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Lung cancer screening and smoking cessation efforts

Dana Moldovanu, Harry J. de Koning, Carlijn M. van der Aalst

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Concurrent chemoradiotherapy for stage III non-small-cell lung cancer: recent progress and future perspectives (a narrative review)

Małgorzata Łazar-Poniatowska, Artur Bandura, Rafał Dziadziuszko, Jacek Jassem

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Dose and fractionation schedules in radiotherapy for non-small cell lung cancer

Lucyna Kepka, Joanna Socha

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Controversies in the role of radiotherapy in pleural mesothelioma

Gerard G. Hanna, Thomas John, David L. Ball

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Preoperative and postoperative radiotherapy (RT) for non-small cell lung cancer: still an open question

Paul Van Houtte, Luigi Moretti, Florian Charlier, Martine Roelandts, Dirk Van Gestel

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Exploring natural killer cell immunology as a therapeutic strategy in lung cancer

Jonas B. Hess, Kate D. Sutherland, Sarah A. Best

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Thoracic radiotherapy in small cell lung cancer—a narrative review

Antonin Levy, Angela Botticella, Cécile Le Péchoux, Corinne Faivre-Finn

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Participation in lung cancer screening

David R. Baldwin, Kate Brain, Samantha Quaife

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Managing screening-detected subsolid nodules—the Asian perspective

Masaaki Sato, Shun-Mao Yang, Dong Tian, Nakajima Jun, Jang-Ming Lee

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Evolving target volume concepts in locally advanced non-small cell lung cancer

Ursula Nestle, Cecile Le Pechoux, Dirk De Ruysscher

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The radiologist’s role in lung cancer screening

Annemiek Snoeckx, Caro Franck, Mario Silva, Mathias Prokop, Cornelia Schaefer-Prokop, Marie-Pierre Revel

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Implementation of lung cancer screening: what are the main issues?

Carlijn M. van der Aalst, Kevin ten Haaf, Harry J. de Koning, for the 4-IN-THE-LUNG-RUN Consortium

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Is there any opportunity for immune checkpoint inhibitor therapy in non-small cell lung cancer patients with brain metastases?

Lizza E. L. Hendriks, Jordi Remon, Jessica Menis, Benjamin Besse

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Holding our breath: the promise of tissue-resident memory T cells in lung cancer

Claire Marceaux, Clare E. Weeden, Claire L. Gordon, Marie-Liesse Asselin-Labat

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Exploring the immune-checkpoint inhibitors’ efficacy/tolerability in special non-small cell lung cancer (NSCLC) populations: focus on steroids and autoimmune disease

Francesco Passiglia, Valeria Cetoretta, Marco De Filippis, Valerio Napoli, Silvia Novello

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The knowns & unknowns of pulmonary toxicity following immune checkpoint inhibitor therapies: a narrative review

Alistair R. Miller, Renee Manser

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Thermal ablation in non-small cell lung cancer: a review of treatment modalities and the evidence for combination with immune checkpoint inhibitors

Kanishka Rangamuwa, Tracy Leong, Clare Weeden, Marie-Liesse Asselin-Labat, Steven Bozinovski, Michael Christie, Tom John, Phillip Antippa, Louis Irving, Daniel Steinfort

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Lung cancer screening: targeting the hard to reach—a review

Guido Van Hal, Paloma Diab Garcia

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Immunotherapy in oncogene addicted non-small cell lung cancer

Luke McLean, Jose Luis Leal, Benjamin J. Solomon, Thomas John

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Latest CT technologies in lung cancer screening: protocols and radiation dose reduction

Marleen Vonder, Monique D. Dorrius, Rozemarijn Vliegenthart

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Stereotactic radiotherapy for early stage non-small cell lung cancer: current standards and ongoing research

Eugenia Vlaskou Badra, Michael Baumgartl, Silvia Fabiano, Aurélien Jongen, Matthias Guckenberger

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Artificial intelligence for detection and characterization of pulmonary nodules in lung cancer CT screening: ready for practice?

Anton Schreuder, Ernst T. Scholten, Bram van Ginneken, Colin Jacobs

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Integrating endobronchial ultrasound bronchoscopy with molecular testing of immunotherapy biomarkers in non-small cell lung cancer

Steven Bozinovski, Amanda Vannitamby, Kanishka Rangamuwa, Savreet Aujla, Hao Wang, Christian Aloe, Louis Irving, Tracy T. Leong, Daniel P. Steinfort

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Immunotherapy in small cell lung cancer: one step at a time: a narrative review

Daphne W. Dumoulin, Anne-Marie C. Dingemans, Joachim G. J. V. Aerts, Jordi Remon, Dirk K. M. De Ruysscher, Lizza E. L. Hendriks

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Implementation of low-dose CT screening in two different health care systems: Mount Sinai Healthcare System and Phoenix VA Health Care System

Claudia I. Henschke, David F. Yankelevitz, Artit Jirapatnakul, Rowena Yip, Vivian Reccoppa, Charlene Benjamin, Tserling Llamo, Angel Williams, Simon Liu, Daniel Max, Samuel M. Aguayo, Providencia Morales, Brian J. Igel, Hamed Abbaszadegan, Peter A. Fredricks, Daniel P. Garcia, Paska A. Permana, Janet Fawcett, Samir Sultan, Lorenza A. Murphy

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Review Article

Added benefits of early detection of other diseases on low-dose CT screening

Rowena Yip, Artit Jirapatnakul, Minxia Hu, Xiangmeng Chen, Dan Han, Teng Ma, Yeqing Zhu, Mary M. Salvatore, Laurie R. Margolies, David F. Yankelevitz, Claudia I. Henschke, for the I-ELCAP Investigators

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