Original Article

A cohort study of the efficacy and safety of immune checkpoint inhibitors plus anlotinib versus immune checkpoint inhibitors alone as the treatment of advanced non-small cell lung cancer in the real world

Yue Shi, Min Ji, Yingying Jiang, Rong Yin, Zihan Wang, Hang Li, Shuaiyu Wang, Kang He, Yuxin Ma, Zhitong Wang, Jianwei Lu, Meiqi Shi, Bo Shen, Guoren Zhou, Tracy L. Leong, Xiaohua Wang, Cheng Chen, Jifeng Feng

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Feasibility and safety of pedicled autologous bronchial flap reconstruction airway instead of sleeve lobectomy in partial lung cancer surgery

Zheng Zhang, Xiaonu Peng, Bo Ai, Kuo Li, Yang Li, Fernando C. Abrão, Hitoshi Igai, Ricardo Mingarini Terra, Han Xiao, Quanfu Huang, Yongde Liao

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Predictive performance of selected breath volatile organic carbon compounds in stage 1 lung cancer

Ekaterina Smirnova, Christopher Mallow, John Muschelli, Yuan Shao, Jeffrey Thiboutot, Andres Lam, Ana M. Rule, Ciprian Crainiceanu, Lonny Yarmus

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Comparison of the perioperative outcomes between robotic-assisted thoracic surgery and video-assisted thoracic surgery in non-small cell lung cancer patients with different body mass index ranges

Chenghao Qu, Rongyang Li, Zheng Ma, Jingyi Han, Weiming Yue, Clemens Aigner, Monica Casiraghi, Hui Tian

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Osimertinib in non-small cell lung cancer with uncommon EGFR-mutations: a post-hoc subgroup analysis with pooled data from two phase II clinical trials

Inger Johanne Zwicky Eide, Simone Stensgaard, Åslaug Helland, Simon Ekman, Anders Mellemgaard, Karin Holmskov Hansen, Saulius Cicenas, Jussi Koivunen, Bjørn Henning Grønberg, Boe Sandahl Sørensen, Odd Terje Brustugun

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A random forest algorithm predicting model combining intraoperative frozen section analysis and clinical features guides surgical strategy for peripheral solitary pulmonary nodules

Liqiang Qian, Yinjie Zhou, Wanqin Zeng, Xiaoke Chen, Zhengping Ding, Yujia Shen, Yifeng Qian, Davide Tosi, Mario Silva, Yuchen Han, Xiaolong Fu

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Malignant pleural mesothelioma nodules remodel their surroundings to vascularize and grow

Ildiko Kovacs, Edina Bugyik, Katalin Dezso, Julia Tarnoki-Zach, Elod Mehes, Marton Gulyas, Andras Czirok, Elisabeth Lang, Michael Grusch, Karin Schelch, Balazs Hegedus, Ildiko Horvath, Nandor Barany, Zsolt Megyesfalvi, Anna Tisza, Zoltan Lohinai, Mir Alireza Hoda, Konrad Hoetzenecker, Francesco Pezzella, Sandor Paku, Viktoria Laszlo, Balazs Dome

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Phase II study of nanoparticle albumin-bound paclitaxel monotherapy for relapsed non-small cell lung cancer with patient- reported outcomes (NLCTG1302)

Satoshi Shoji, Satoru Miura, Satoshi Watanabe, Aya Ohtsubo, Koichiro Nozaki, Yu Saida, Kosuke Ichikawa, Rie Kondo, Tomohiro Tanaka, Kenichi Koyama, Hiroshi Tanaka, Masaaki Okajima, Tetsuya Abe, Takeshi Ota, Takashi Ishida, Masato Makino, Akira Iwashima, Kazuhiro Sato, Naoya Matsumoto, Hirohisa Yoshizawa, Toshiaki Kikuchi

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Correlation of tumor microenvironment-related markers with clinical outcomes in patients with squamous cell carcinoma of the lung

Mayu Sugai, Naoki Yanagawa, Shunsuke Shikanai, Mai Hashimoto, Hirotaka Saikawa, Mitsumasa Osakabe, Hajime Saito, Makoto Maemondo, Tamotsu Sugai

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Totality outcome of afatinib sequential treatment in patients with EGFR mutation-positive non-small-cell lung cancer in South Korea (TOAST): Korean Cancer Study Group (KCSG) LU-19-22

Hyun Ae Jung, Min Hee Hong, Hyun Woo Lee, Kyung Hee Lee, Il Hwan Kim, Young Joo Min, Hee Kyung Ahn, Byoung Yong Shim, Yoon Hee Choi, Yun-Gyoo Lee, Jeong A Kim, Joung Soon Jang, Seong-Hoon Shin, Keon Uk Park, Jin Hyoung Kang, Keunchil Park

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The procedure and effectiveness of release maneuvers in tracheobronchial resection and reconstruction

Jiaxi He, Yunpeng Zhong, Hon-Chi Suen, Aditya Sengupta, Raghav A. Murthy, Eirch Stoelben, Angelo Carretta, Alper Toker, Chudong Wang, Jianxing He, Shuben Li

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Comprehensive analysis of mutational profile and prognostic significance of complex glandular pattern in lung adenocarcinoma

Jinsong Bai, Chaoqiang Deng, Qiang Zheng, Di Li, Fangqiu Fu, Yuan Li, Yang Zhang, Haiquan Chen

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Re-evaluating the need for mediastinal lymph node dissection and exploring lncRNAs as biomarkers of N2 metastasis in T1 lung adenocarcinoma

Xuefeng Hao, Weiying Li, Wei Li, Meng Gu, Ziyu Wang, Kenta Nakahashi, Mara B. Antonoff, Hiroyuki Adachi, Shijie Zhou, Shaofa Xu

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Efficacy and safety of camrelizumab plus apatinib in previously treated patients with advanced non-small cell lung cancer harboring EGFR or ALK genetic aberration

Guanghui Gao, Jian Ni, Yina Wang, Shengxiang Ren, Zhihua Liu, Gongyan Chen, Kangsheng Gu, Aimin Zang, Jun Zhao, Renhua Guo, Jianxing He, Xiaoyan Lin, Yueyin Pan, Zhiyong Ma, Zhehai Wang, Min Fan, Yunpeng Liu, Shundong Cang, Xinfeng Yang, Weixia Li, Quanren Wang, Caicun Zhou

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Tolerability, safety, and preliminary antitumor activity of fuzuloparib in combination with SHR-1316 in patients with relapsed small cell lung cancer: a multicenter, open-label, two-stage, phase Ib trial

Yanjun Xu, Zhiyu Huang, Jian Fang, Anwen Liu, Hongyang Lu, Xinmin Yu, Kaiyan Chen, Xiaoling Xu, Xinjing Ma, Wei Shi, Young Hak Kim, Taiki Hakozaki, Alfredo Addeo, Yu Shen, Shaorong Li, Yun Fan

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Efficacy, prognosis and safety analysis of anti-PD-1/PD-L1 inhibitor rechallenge in advanced lung cancer patients: a cohort study

Jin Yang, Ran Zeng, Jianping Zhou, Lifeng Luo, Mengchen Lyu, Fang Liu, Xianwen Sun, Ling Zhou, Xiaofei Wang, Zhiyao Bao, Wei Chen, Daphne W. Dumoulin, Beili Gao, Yi Xiang

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Immune checkpoint inhibitor (ICI)-based treatment beyond progression with prior immunotherapy in patients with stage IV non-small cell lung cancer: a retrospective study

Tian Tian, Min Yu, Yang Yu, Ke Wang, Panwen Tian, Ziyue Luo, Zhenyu Ding, Ye Wang, Youling Gong, Jiang Zhu, Bingwen Zou, Terence T. Sio, Adelaide Alves, Yongmei Liu, Meijuan Huang, You Lu

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Targeting STT3A produces an anti-tumor effect in lung adenocarcinoma by blocking the MAPK and PI3K/AKT signaling pathway

Jiahan Cheng, Liang Xia, Xiaohu Hao, Fanyi Gan, Yuquan Bai, Chuanfen Zhang, Yonghong Mao, Yunke Zhu, Qiang Pu, Dong Won Park, Simona Tavolari, Jiandong Mei, Yaohui Chen, Senyi Deng, Lunxu Liu

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Clinicopathological characteristics and prognostic significance of HDAC11 protein expression in non-small cell lung cancer: a retrospective study

Di Lu, Zhiqiang Ma, Di Huang, Jundong Zhang, Jinfeng Li, Peng Zhi, Lizhong Zhang, Yingtong Feng, Xiangwei Ge, Jinzhao Zhai, Menglong Jiang, Xin Zhou, Charles B. Simone II, Joel W. Neal, Shruti Rajesh Patel, Xiaolong Yan, Yi Hu, Jinliang Wang

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Intraoperative methods for wrapping anastomoses after airway reconstruction: a case series

Chudong Wang, Junguo Dong, Xiaoxue Zhuang, Chao Yang, Hanzhang Chen, Terunaga Inage, Jeffrey B. Velotta, Alessandro Brunelli, Takahiro Homma, Norihisa Shigemura, Hon Chi Suen, Jianxing He, Shuben Li

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Partitioning the lung field based on the depth ratio in three-dimensional space

Jingjing Huang, Chengyu Bian, Wenhao Zhang, Guang Mu, Zhipeng Chen, Yang Xia, Mei Yuan, Hideki Ujiie, Jean H. T. Daemen, Erik R. de Loos, Quan Zhu, Weibing Wu, Liang Chen, Jun Wang

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Review Article

A narrative review of deep learning applications in lung cancer research: from screening to prognostication

Jong Hyuk Lee, Eui Jin Hwang, Hyungjin Kim, Chang Min Park

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The treatment of advanced non-small cell lung cancer harboring KRAS mutation: a new class of drugs for an old target—a narrative review

Alessia Spagnuolo, Paolo Maione, Cesare Gridelli

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Comparative characteristics of small cell lung cancer and Ewing’s sarcoma: a narrative review

Gerhard Hamilton

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Letter to the Editor

Shift in lung cancer stage at diagnosis during the COVID-19 pandemic in New York City

Raja Flores, Naomi Alpert, Ken McCardle, Emanuela Taioli

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Case Report

Anti-Zic4 paraneoplastic cerebellar degeneration in a patient with EGFR-mutated NSCLC: a case report

Javier Pozas, Víctor Albarrán-Fernández, Luis González-Campo, María Eugenia Olmedo-García, Elena Corral de la Fuente, Iñigo Corral-Corral, Ángela Carrasco, Teresa Alonso-Gordoa, Javier Molina-Cerrillo, Yolanda Lage-Alfranca, Ana Gómez-Rueda, Pilar Garrido

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Study Protocol

Prospective evaluation of immunological, molecular-genetic, image-based and microbial analyses to characterize tumor response and control in patients with unresectable stage III NSCLC treated with concurrent chemoradiotherapy followed by consolidation therapy with durvalumab (PRECISION): protocol for a prospective longitudinal biomarker study

Lukas Käsmann, Julian Taugner, Chukwuka Eze, Alexander Nieto, Carolyn Pelikan, Benedikt Flörsch, Saskia Kenndoff, Thomas P. Hofer, Elfriede Nössner, Christian Schulz, Marcus Unterrainer, Amanda Tufman, Frederick Klauschen, Andreas Jung, Jens Neumann, Jörg Kumbrink, Niels Reinmuth, Peter Bartenstein, Claus Belka, Farkhad Manapov

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iMDT Corner

Metastatic pulmonary carcinoids with EML4-ALK fusion response to ALK inhibitors: two case reports and review of literature

Xi Lei, Shuai Zhu, Dian Ren, Fan Ren, Tong Li, Ning Zhou, Shuo Li, Tao Shi, Lingling Zu, Zuoqing Song, Justyna Chalubinska-Fendler, Marc G. Denis, Eric H. Bernicker, Vincent Thomas de Montpréville, Richeng Jiang, Song Xu

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