Publish Ahead of Print

Original Article

Artificial intelligence-based analysis for immunohistochemistry staining of immune checkpoints to predict resected non-small cell lung cancer survival and relapse
Haoyue Guo, Li Diao, Xiaofeng Zhou, Jie-Neng Chen, Yue Zhou, Qiyu Fang, Yayi He, Rafal Dziadziuszko, Caicun Zhou, Fred R. Hirsch
Pleural effusions associated with squamous cell lung carcinoma have a low diagnostic yield and a poor prognosis
Michael Dorry, Kevin Davidson, Rajesh Dash, Rachel Jug, Jeffrey M. Clarke, Andrew B. Nixon, Kamran Mahmood
One carbon metabolism in human lung cancer
Sha Yao, Luogen Peng, Omar Elakad, Stefan Küffer, Marc Hinterthaner, Bernhard C. Danner, Alexander von Hammerstein-Equord, Philipp Ströbel, Hanibal Bohnenberger
The clinical impact of three validated PD-L1 immunohistochemistry assays as a prognostic factor in small cell lung cancer
Yong Seok Lee, Jun Hyeok Lim, Wookyung Ryu, Mi Hwa Park, Lucia Kim, Kang Kim, Woo Youl Kim, Hae-Seong Nam
Differences in treatment effect size between progression-free survival and overall survival in anti-PD-1/PD-L1 inhibitors-based trials in advanced NSCLC: a systematic review and meta-analysis
Zhirui Zhou, Shengxiang Ren, Lingxiao Chen, Caicun Zhou, Tao Jiang
PD-L1 detection on circulating tumor-derived extracellular vesicles (T-EVs) from patients with lung cancer
Fei Wu, Yanzi Gu, Bin Kang, Fabienne Heskia, Alexandre Pachot, Marc Bonneville, Ping Wei, Ji Liang
Immune checkpoint inhibitors in oncogene-addicted non-small cell lung cancer: a systematic review and meta-analysis
Giorgia Guaitoli, Marcello Tiseo, Massimo Di Maio, Luc Friboulet, Francesco Facchinetti
Increased plasma levels of damage-associated molecular patterns during systemic anticancer therapy in patients with advanced lung cancer
Hiroyuki Inoue, Hirono Tsutsumi, Kentaro Tanaka, Eiji Iwama, Yoshimasa Shiraishi, Aiko Hirayama, Takayuki Nakanishi, Hiroyuki Ando, Maako Nakajima, Seiji Shinozaki, Hiroaki Ogata, Kazuyasu Uryu, Koji Okamura, Shinichi Kimura, Tomohiro Ogawa, Keiichi Ota, Yasuto Yoneshima, Naoki Hamada, Yoichi Nakanishi, Isamu Okamoto
First-line immunotherapy in non-small cell lung cancer patients with poor performance status: a systematic review and meta-analysis
Francesco Facchinetti, Massimo Di Maio, Fabiana Perrone, Marcello Tiseo
Should resection extent be decided by total lesion size or solid component size in ground glass opacity-containing lung adenocarcinomas?
Boyu Lin, Rui Wang, Liang Chen, Zhitao Gu, Chunyu Ji, Wentao Fang
Different prognostic implications of hepatic metastasis according to front-line treatment in non-small cell lung cancer: a real-world retrospective study
Myeong Geun Choi, Chang-Min Choi, Dae Ho Lee, Sang-We Kim, Shinkyo Yoon, Woo Sung Kim, Wonjun Ji, Jae Cheol Lee

Review Article

Immunotherapy in small cell lung cancer: one step at a time: a narrative review
Daphne W. Dumoulin, Anne-Marie C. Dingemans, Joachim G. J. V. Aerts, Jordi Remon, Dirk K. M. De Ruysscher, Lizza E. L. Hendriks
A narrative review of combined stereotactic ablative radiotherapy and immunotherapy in metastatic non-small cell lung cancer
Zarique Z. Akanda, Paul J. Neeson, Thomas John, Stephen Barnett, Gerard G. Hanna, Alistair Miller, Ross Jennens, Shankar Siva
Novel patterns of progression upon immunotherapy in other thoracic malignancies and uncommon populations
Roberto Ferrara, Diego Signorelli, Claudia Proto, Arsela Prelaj, Marina Chiara Garassino, Giuseppe Lo Russo
Is there any opportunity for immune checkpoint inhibitor therapy in non-small cell lung cancer patients with brain metastases?
Lizza E. L. Hendriks, Jordi Remon, Jessica Menis, Benjamin Besse
Exploring natural killer cell immunology as a therapeutic strategy in lung cancer
Jonas B. Hess, Kate D. Sutherland, Sarah A. Best
How to optimize the incorporation of immunotherapy in trials for oligometastatic non-small cell lung cancer: a narrative review
Jordi Remon, Jessica Menis, Antonin Levy, Dirk K. M. De Ruysscher, Lizza E. L. Hendriks
Local ablative therapy in oncogenic-driven oligometastatic non-small cell lung cancer: present and ongoing strategies—a narrative review
Vincent Fallet, Lise Matton, Antoine Schernberg, Anthony Canellas, François H. Cornelis, Jacques Cadranel
A narrative review of the migration and invasion features of non-small cell lung cancer cells upon xenobiotic exposure: insights from in vitro studies
Catarina Albuquerque, Rita Manguinhas, João G. Costa, Nuno Gil, Jordi Codony-Servat, Matilde Castro, Joana P. Miranda, Ana S. Fernandes, Rafael Rosell, Nuno G. Oliveira
Holding our breath: the promise of tissue-resident memory T cells in lung cancer
Claire Marceaux, Clare E. Weeden, Claire L. Gordon, Marie-Liesse Asselin-Labat
The knowns & unknowns of pulmonary toxicity following immune checkpoint inhibitor therapies: a narrative review
Alistair R. Miller, Renee Manser
Radiotherapy for oligometastatic non-small cell lung cancer: a narrative review
Nora Sundahl, Yolande Lievens
Has programmed cell death ligand-1 MET an accomplice in non-small cell lung cancer? A narrative review
Wolfram C. M. Dempke, Klaus Fenchel
Current and future research efforts in oligometastatic non-small cell lung cancer—a systematic review
Mariana Brandão, Valérie Durieux, Thierry Berghmans
Consistency of recommendations for the diagnosis and treatment of non-small cell lung cancer: a systematic review
Zhe Zhang, Sen Yang, Yanfang Ma, Hanqiong Zhou, Xuan Wu, Jing Han, Jiabao Hou, Lidan Hao, Jonathan D. Spicer, Young Wha Koh, Mariano Provencio, Noemi Reguart, Tetsuya Mitsudomi, Qiming Wang
Immunotherapy in oncogene addicted non-small cell lung cancer
Luke McLean, Jose Luis Leal, Benjamin J. Solomon, Thomas John
A narrative review on tumor microenvironment in oligometastatic and oligoprogressive non-small cell lung cancer: a lot remains to be done
Lorenzo Belluomini, Alessandra Dodi, Alberto Caldart, Dzenete Kadrija, Marco Sposito, Miriam Casali, Giulia Sartori, Miriam Grazia Ferrara, Alice Avancini, Emilio Bria, Jessica Menis, Michele Milella, Sara Pilotto
Narrative review of immunotherapy in thymic malignancies
Jose Carlos Benitez, Benjamin Besse
Integrating endobronchial ultrasound bronchoscopy with molecular testing of immunotherapy biomarkers in non-small cell lung cancer
Steven Bozinovski, Amanda Vannitamby, Kanishka Rangamuwa, Savreet Aujla, Hao Wang, Christian Aloe, Louis Irving, Tracy T. Leong, Daniel P. Steinfort
Thermal ablation in non-small cell lung cancer: a review of treatment modalities and the evidence for combination with immune checkpoint inhibitors
Kanishka Rangamuwa, Tracy Leong, Clare Weeden, Marie-Liesse Asselin-Labat, Steven Bozinovski, Michael Christie, Tom John, Phillip Antippa, Louis Irving, Daniel Steinfort
Current and future biomarkers for outcomes with immunotherapy in non-small cell lung cancer
Boris Duchemann, Jordi Remon, Marie Naigeon, Lydie Cassard, Jean Mehdi Jouniaux, Lisa Boselli, Jonathan Grivel, Edouard Auclin, Aude Desnoyer, Benjamin Besse, Nathalie Chaput
B cells in lung cancer—not just a bystander cell: a literature review
Tracy L. Leong, Vanessa L. Bryant
Local ablative therapies in oligometastatic NSCLC-upfront or outback?—a narrative review
Michael C. Tjong, Alexander V. Louie, Puneeth Iyengar, Benjamin J. Solomon, David A. Palma, Shankar Siva
Exploring the immune-checkpoint inhibitors’ efficacy/tolerability in special non-small cell lung cancer (NSCLC) populations: focus on steroids and autoimmune disease
Francesco Passiglia, Valeria Cetoretta, Marco De Filippis, Valerio Napoli, Silvia Novello
Emerging and multifaceted role of neutrophils in lung cancer
Christian Aloe, Hao Wang, Ross Vlahos, Louis Irving, Daniel Steinfort, Steven Bozinovski
Clinical prognostic factors in surgically treated oligometastatic non-small cell lung cancer: a systematic review
Luca Bertolaccini, Monica Casiraghi, Giulia Sedda, Filippo de Marinis, Lorenzo Spaggiari
The multiple roles and therapeutic potential of clusterin in non-small-cell lung cancer: a narrative review
Juofang Tan, Wei Guo, Su Yang, Dingpei Han, Hecheng Li
Immunotherapy in malignant pleural mesothelioma: a review of literature data
Jessica Menis, Giulia Pasello, Jordi Remon


Local for advanced, is this a paradox?
Maristella Bungaro, Chiara Paratore, Paolo Bironzo, Silvia Novello

Brief Report

Increase in tumour PD-L1 expression in non-small cell lung cancer following bronchoscopic thermal vapour ablation
Kanishka Rangamuwa, Tracy Leong, Steven Bozinovski, Michael Christie, Thomas John, Phillip Antippa, Louis Irving, Daniel Steinfort

Editorial on Immunotherapy in Other Thoracic Malignancies and Uncommon Populations

Immunotherapy in other thoracic malignancies and uncommon populations
Jordi Remon, Benjamin Besse