Article Abstract

Stressing the need to overcome EGFR tyrosine kinase inhibitor resistance

Authors: Leila Toulabi, Bríd M. Ryan


Lung cancer remains the leading cause of cancer-related mortality (1). This is partly due to the late stage at which lung cancer is diagnosed—more than 80% of lung cancers are diagnosed with either regional or distant metastasis (1). However, it is also partly because many patients’ tumors are ultimately refractory to therapy.