Broad-based genomic sequencing in advanced non-small cell lung cancer in the dock

Caterina Fumagalli, Elena Guerini-Rocco, Massimo Barberis


The recently published study of Presley and colleagues (1) aimed to ascertain if there is an association between broad-based genomic sequencing (defined as multigene Next-Generation Sequencing panels of 30 or more genes) and better survival in patients with advanced non-small cell lung cancer (NSCLC). For this purpose, the authors retrospectively analyzed data obtained from medical records of a large cohort of patients (n=5,688) with NSCLC from January 2011 to July 2016, treated in 191 community oncology practices across the United States.