Article Abstract

Lung neuroendocrine tumors: a new addition to the evolving list of spread through air spaces

Authors: Hironori Uruga, Mari Mino-Kenudson

Abstract

Air-filled spaces are a notable characteristic of the lung. When a cancer develops in the lung, it is often surrounded by air spaces; thus, there is the possibility that cancer cells spread thorough air spaces. In fact, Kodama and colleagues presented a lung cancer case with multifocal “aerogenous” spread in 1980 and ultrastructurally studied the nature of detached fragments (1).

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